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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c09118c7b96b7050e0f5cb5b7bc3825dc9c08037fa071232bf93d2cb7274e7' 
  AND token = 'DhX4DXUtvS2CAuhEEuOT0CNKLChqkT97aglUhicbUZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}