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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503463976cd96bfeee8b958f29cff1cb1a73cc76852f23ce2b0bdd93b531e3e8' 
  AND token = 'UaF4TwfyH0XLSZD76AS8TWKMReo1NXUjGplZ2xZG5RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}