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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cace4d0798e41e375145453229ca39c03bf844e97d99cfb6d439b14db677369' 
  AND token = 'oKd/FfsfKLgCRH6syUrfTgKTs6SGwxMJHedNsEBddFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}