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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91d78da53af343764b8d447016d5fe59a5b8d9524ade7be7bc47e5fe473a3563' 
  AND token = 'IUg12fZaUOs1P6tEwiPzjCO6K8GUxzLGO86Aozxwli0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}