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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379c576c22a2b6f35c07402bfa52eeb77b36d3fe1f54189a0f97e4b222c0d10b' 
  AND token = 'r0Bl1KtDywWjx7ilVkHJ7l5Nq2jywUXfvlLKjQlqeuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}