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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b0a362057bec795e568373d2423775b51263adb7f779fa065355ae031d68b8' 
  AND token = 'x9cRlzyqfEuV0/pye3VJ9PYhC+n0N++yHQ2PxMokOac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}