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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8866261cdc8f01d9557e7faab49b2129cdc06443ee3b9d9606849c925228df2c' 
  AND token = '2tHSZa6nggv3a3CFTJgmqk9qaNFcU5lVNqLDorlgCYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}