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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa46edd8b3e3cc430c74a386ae28acd6648e0a739464998e34ff781221b2046' 
  AND token = 'fvY08OPAkSzBYA9WYP+RhiklT5GzVmD/0vI1V2fIRAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}