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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '578302f9a1fa63b99fdf59d7415a722ad7cedf4f5e8c79deef3e868c32c1f61c' 
  AND token = 'RpLVT8NYvbDqVzsyN2FXJQkGmJFzFb4FJ0Ord6aMoJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}