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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9666d4843f1c4e2feccca3edcff53c9c917a779f51352c225feb3df1903846' 
  AND token = '2Zto/rASIwb/KFEmtzdQimwUDhzJywm6ZlT0DMWAYAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}