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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16658336501ceef979ead4c78533ae6f37d93e8d416758e04e7f847c69cfd05e' 
  AND token = 'nRrZHzOd0t+umoeZiVoAoHIR1/HCOrbz7qi7g5wpueU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}