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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b20c4206a5ec82cb1585cc0c5c6b8335d410427a61fca613c742f1fb5d9558' 
  AND token = 'X2hVIqT6oj9IJxDVezxlvYRISu8gsV1nndI+jfWd34g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}