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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78115864d40f2685aeead712fc688e78805ad5239614d45a3445055c345b64c3' 
  AND token = 'viLa7+fyGqR1hb6TU+JoxuT3joj0/w6Kxqru0ePdT+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}