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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d0f32d9c9ca43c74b93a9fc6e9275029d10013648a2837fad0b738300f2172' 
  AND token = 'gYF2MHRDBALNrtvz7w/n4R4+fbCskFX3Nrap6B+buiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}