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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '285f4e4d53479ac076f09da6cd02dbf093a6d4ac588b0e4414b0d58bbcb13b30' 
  AND token = 'PbVtSWYPsvVSurJ7GS/TZbIJV5qTHJ4DBFh9f0ixPmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}