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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eeebf88b37b4b0bc69b56257fd00fd4f25fedd148e560f566e329344bb4a04d' 
  AND token = 'igKlhdId3nbg6Z0vXqBDz0DSJ3eWtlFk2FA3DXuYZIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}