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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21563bacbefe4bcdfa27c3aac9e9b8dc4e275a57cc81d2268bcc53f3bdd7729b' 
  AND token = 'SJkoYZC2WPDi86INfhkfkzPFsPao4vtVyxzF3OxZXnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}