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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295c53def859321d47120c53cdcefbf74d77584f00d6e1f75959358038cf60ee' 
  AND token = 'TeMDRbu2EtCX9XD0Uf+QUaZBQwNHmi82g12MRiZj9qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}