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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c667b535af6478abcf94068cf501748a3728e656b588f2531d482ba6f1d0f8a5' 
  AND token = 'YYT1YjaQDFhFAPGZ2Ub+rTPn2s/QTXiXGBaRYBMBnMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}