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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff373aa6abea7c3bf1cf43d1ce76d5ead243ceb1f51efcf85a920955b3083640' 
  AND token = 'M89zC3/+2OkyZVZJyyRqx1Mzs9jcOz0MEbL4v7H4WaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}