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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80bf9375a9d0185730788850232e5f4d1a809917db9bfcc478bf52016a4f787' 
  AND token = '7ViAmOA/KVqKgDlPVVcJeCHEvhRMaVB8O9Tz6epEt1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}