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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1495f76b263689b882683106b04f2e13fb40387508451bef1286f3b04434b274' 
  AND token = 'LcPi3/gE3qKML1Gw1WpSntXzrh8rFgk1klgtMS7az4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}