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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6d827495e79281f88b13be19ecc050d37a2924241a3b1648e834bf9d82bfbb' 
  AND token = 'EMtQLXymtob5ikV1ZUIOFzKxQHq5tS7BH+7qDN0mC7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}