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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5821a0809b1f7743eb36257cb2952fc1056dab918346e685805cc620cb9d246' 
  AND token = 'HL0H0okyo1vxcuqjOZUI2s31S5HcnP62skcyYhHn4PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}