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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a5e4e85da385855faf444f6aea1c882dff9159826e9a616d6926ed44bd4295c' 
  AND token = 'qXpEwZHTLxbYT8DmTd7g2+HK17CMadZckfz/1X2Nu08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}