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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6b9faef49b0e05894f4ba2d93169da0f14f13fc26770868adbd5aa41007bf24' 
  AND token = 'Op8qhASUX3oUgwoVrmhCZWUn15Pk8Bc8tjfTjPXeW48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}