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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '573aad13d19c5787af513c2d47c2aa45ab0bc34d2cca30db5fbd547e2b4f1c1e' 
  AND token = 'XTNtuAlfHMlLyTU1sgyTf21LPBhtcLH8TU/l+Q4T23E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}