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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06dde94db286aafe270e917f7b698ea9d67956f152d25b5e5644674a01060546' 
  AND token = 'IJWFeI6UNaIBQIqqiImXp9jIdufQtk9qac7doc2H8NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}