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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa279d9207336ab7faa641f966810ec1e2de40f5698553618fa1a4f6ee8fb259' 
  AND token = 'p9AOmJUJ8RqpEHkHelgpG51fFBuvvU3k5T4OzJ6Cxjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}