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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63d409016506d9cf767f84f4071afe48fac55c1d52d29179fa416bc64a5e8463' 
  AND token = 'da1WihdYb6tqMhg5fE9XWIrDBI+wCoRbYBpUvaf5Oj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}