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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdc37e9f93ca9bf4e972371627b22733ff7b8e71775c1e7cfe3309c45e14f587' 
  AND token = 'ITW7bVR1ZrlOW92XWDcd8ecelAUpKbXbpzowcljSIHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}