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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177b7e38a0736a020277cbaf931e9c9a18596bb5804cad961ad4cd81935dd610' 
  AND token = 'PgSFDFaqpCwX5k4Y4QiHJ2TxQljVt0diWDaWd5pkFQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}