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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd67d1426829f2e7e6ee20bebf7009d4a6f27ecd394e75385771799019435a0d' 
  AND token = 'VRGASlSkYE6gZjP56OfvUwuAMyDV9X9IiMXPFhNNk6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}