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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c03b4fc80ce40d73a8b1aab5508c4178a2a4fb4dfa58cea8eac22827850486' 
  AND token = 'nOpRWJw6cDEQhlDXCyyI1YES4lS3dXe9Z0xP6mP2Gt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}