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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '963f136c1de70a464bff651837394d9fa330751bf687ada00a8f336461657959' 
  AND token = 'FXsC7Eel9zr0Ii+AECWdC8Jj7EuTQTvu2+VWV5vPk1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}