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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f73d472f66592e5b702e6fd2f88cf0247fd750e42cfe6d4f34456d97190ad5c5' 
  AND token = '3z7u9VyGWUtNYDBt3lrxoloRLZN1Tyq0WZY/M5dfep8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}