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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9307a8e7064bc2f81ceb99b7521df24728569a7da36eb6a9768915acf7c19323' 
  AND token = 'M158FH1EQwSbNk7pCemosVQCHW2Min8ck4yvWJ+c1hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}