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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bb7e11ad5b0c1fc8d8cea4980ed438fe178414408769facbfe4bdeade6eb3f' 
  AND token = '+3iPYpufuS8pP68CxtIosRGEjGAmYZqDE18B3lB3fFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}