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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '598abc566f4a7f83ff5daf772e61e9d35d24f1f4efc1c0feb85abf391312faf9' 
  AND token = 'rgo4WAsZKHjYjzNdrgjDMnNPkC/rXGyDFsZ+eRMK4kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}