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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6486a2d60fd5e2464b4cfb1472d5744673c0bea6a9cc5a9019097fda26eaf6e' 
  AND token = 'jDTIWeZcfJ8dBEIJj/hZ4YxqeOX8GOVMgyuPJj65O+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}