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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c54e2fa6352a4388ecfe951e32cc2ec05f2866ae1139bbaf168d2d1b10041891' 
  AND token = 'w/F1NEjr/ns2HD7Zql6ZJUpNH+21MX4lya9nhwXRGy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}