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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd7a673c7e36e6a6fcf9acb3ce0f356e64ab66084706fadd4bc6b5b3bac7bb8' 
  AND token = 'qGs+TKw2cKcxroINGNqfix0uSZvjL62fgTgsA3hIYAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}