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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6176d7a7a9aee63d25a81a313c2acdc0bd6f1e39672fb1eb66574fb61880d82f' 
  AND token = 'VVt36K3EhCigJRxPtVxLfKEBXleCuQo+PWsikN6kBFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}