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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '844bb0dad1173060a30730b43aed6cbf349b043fbe1261d0ab1f860b72123acd' 
  AND token = 'MxqlEf/UxrKKQHkcjMOTXQs3VuVdhYpVuHYFurPW1Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}