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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7718d2a8cf6471ed7c78a816c81810bd2d656a971105de39f4afdcc53766897' 
  AND token = 'hsIQ2w/Ynv4vNaQQ3d72GygFIdaQ3suYkYUP/+FAyu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}