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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379aef662e90a50100e61c8c830fb9c3a292c9ede6cc1abd3bf2d0a8554c9ed9' 
  AND token = 'VZX+jsmjz8cZEnw6sf8hrIvO43rwLsq5QEx/hmPJ56s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}