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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3063899a64e32f7ecb0c9b2eb7065e6a81ea402fe08a498e41cffe0c6a646ca5' 
  AND token = 'izrRYVRm844GSD3nMCai9hzkPQcHbEM0Qfn4Gx9nop8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}