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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4842aa5c4b09678e347000e0926403938a4a190c68c5530a1446a7232ec9eaf6' 
  AND token = 'rpr9KyEJBprNgrX97CahHyb/xfbTNo5d6ZGC1WH1+CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}