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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f583072235ee6234d2f2f5ecefe8bda68bd7fc0fb82c56bed81d0fe2659fb0b3' 
  AND token = 'Dw5JfsHYeDLZJJ9oP3bNtgvEAXGOuvnRFtouRplhrQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}