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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6daa2156b1493e9f8fab781ba779c133295effa2cd4509c09e918d3b38eeb50b' 
  AND token = 'iN+YeV3MMehzi/UiOdETL5se+sKrAhrAicw4uu5g/28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}